Fetal Microchimerism: A genetic phenomenon for better or worse

Microchimerism is the presence of a small number of cells that originate from another individual and are therefore genetically distinct from the cells of the host individual. A fetus, while in the womb, sheds stem cells that travel through the shared bloodstream and lodge in tissues of the mother. Here’s a great detailed explanation.

For example, studies have shown that women who give birth to males are left with traces of Y chromosomes in their brains which shows that fetal cells can migrate to the brain of a mother and mature into neurons. And guess what? They stay for life. Those Y chromosomes have been found in women in their elderly years.

It’s an intriguing concept if you think about the possibility of designer babies, a concept that is no longer science fiction, and–if it weren’t for ethical considerations–might be further along than it is. But let’s all agree it is a very near future reality.

So consider the implications of bringing these two biological phenomena together: CRISPR-engineered babies, sluffing off DNA that become part of the mother’s DNA. Sure, it might be a great thing. Maybe those enhanced stem cells will help with healing or repairing organ damage.

But…what if not? What if CRISPR makes a mistake? (Yes, it does.)

And what if that mistake is something horrific? Perhaps a more science-based, less demon-based Rosemary’s Baby? Just sayin.’